Metabolic Adaptations to Six-month Caloric Restriction
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منابع مشابه
The effects of fasting on physiological status and gene expression; an overview
Calorie restriction through ingesting no or minimal amounts of food and caloric beverages for periods of time is called fasting. Fasting can affect body through changing in physical and metabolic adaptations, as well as mineral and hormonal status. However, psychological effects and sometimes medical complications are likely in case of inappropriate fasting. Fasting is associated with changes i...
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OBJECTIVES To determine if caloric restriction (CR) would cause changes in plasma metabolic intermediates in response to a mixed meal, suggestive of changes in the capacity to adapt fuel oxidation to fuel availability or metabolic flexibility, and to determine how any such changes relate to insulin sensitivity (S(I)). METHODS Forty-six volunteers were randomized to a weight maintenance diet (...
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We have previously shown that the proliferative response of T cells to antigenic or mitogenic stimulus decreased with age and that caloric resection (CR) attenuated the age-related decline in proliferation and IL-2 expression. Because activation-induced apoptosis is known to regulate cell proliferation and eliminate the high number of activated cells during an immune response, it was of interes...
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Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease (CLD). Omega-3 fatty acids and antioxidants co-supplementation have been considered as an alternative treatment in NAFLD. This trial will evaluate camelina sativa oil (CSO) effects as a rich source of omega-3 fatty acids and antioxidants on cardiometabolic risk factors, metabolic endotoxemia, liver en...
متن کاملTRANSLATIONAL PHYSIOLOGY Metabolic adaptations to fasting and chronic caloric restriction in heart, muscle, and liver do not include changes in AMPK activity
Gonzalez, Asensio A., Reetu Kumar, Jacob D. Mulligan, Ashley J. Davis, Richard Weindruch, and Kurt W. Saupe. Metabolic adaptations to fasting and chronic caloric restriction in heart, muscle, and liver do not include changes in AMPK activity. Am J Physiol Endocrinol Metab 287: E1032–E1037, 2004. First published July 13, 2004; doi:10.1152/ajpendo.00172.2004.—Activation of adenosine monophosphate...
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